Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03UXO
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| Former ID |
DIB020539
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| Drug Name |
NKY80
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| Synonyms |
NKY 80; NKY-80; adenylyl cyclase type V Inhibitor
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C12H11N3O2
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| Canonical SMILES |
C1C(CC(=O)C2=CN=C(N=C21)N)C3=CC=CO3
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| InChI |
1S/C12H11N3O2/c13-12-14-6-8-9(15-12)4-7(5-10(8)16)11-2-1-3-17-11/h1-3,6-7H,4-5H2,(H2,13,14,15)
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| InChIKey |
SOJUSNIBPPMLCC-UHFFFAOYSA-N
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| CAS Number |
CAS 299442-43-6
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| PubChem Compound ID | ||||
| PubChem Substance ID |
3206944, 3426246, 4020966, 4255985, 5264677, 8306883, 14749298, 25631865, 26758155, 39869056, 47292691, 47961417, 49906453, 57565485, 57680929, 78476736, 88227362, 92153338, 104848727, 111387498, 117675838, 117930575, 124614551, 124840207, 125613856, 135601422, 143406492, 144046493, 160978539, 163016093, 163688673, 164036276, 170222105, 178101917, 179216184, 196376347, 204413421, 208265337, 218604925, 223379692, 225226419, 231805875, 242260337, 243962717, 252158577
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Adenylate cyclase type 5 (AC5) | Target Info | Inhibitor | [2] |
| References | Top | |||
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| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5233). | |||
| REF 2 | Type-specific regulation of adenylyl cyclase. Selective pharmacological stimulation and inhibition of adenylyl cyclase isoforms. J Biol Chem. 2001 Dec 21;276(51):47785-93. | |||
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