Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03SUQ
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| Drug Name |
Apilimod dimesylate
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| Indication | Non-hodgkin lymphoma [ICD-11: 2B33.5; ICD-10: C85.9] | Phase 2 | [1] | |
| Company |
LAM Therapeutics Guilford, CT
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| Structure |
 |
Download2D MOL
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| Formula |
C25H34N6O8S2
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| Canonical SMILES |
CC1=CC(=CC=C1)C=NNC2=CC(=NC(=N2)OCCC3=CC=CC=N3)N4CCOCC4.CS(=O)(=O)O.CS(=O)(=O)O
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| InChI |
1S/C23H26N6O2.2CH4O3S/c1-18-5-4-6-19(15-18)17-25-28-21-16-22(29-10-13-30-14-11-29)27-23(26-21)31-12-8-20-7-2-3-9-24-20;2*1-5(2,3)4/h2-7,9,15-17H,8,10-14H2,1H3,(H,26,27,28);2*1H3,(H,2,3,4)/b25-17+;;
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| InChIKey |
GAJWNIKZLYZYSY-OKUPSQOASA-N
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| CAS Number |
CAS 870087-36-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Phosphatidylinositol-3-phosphate 5-kinase (PIP5K3) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Inositol phosphate metabolism | |||
| Metabolic pathways | ||||
| Phosphatidylinositol signaling system | ||||
| Phagosome | ||||
| Regulation of actin cytoskeleton | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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