Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03RZV
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| Former ID |
DAP000477
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| Drug Name |
Tolazoline
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| Synonyms |
Artonil; Benzalolin; Benzazoline; Benzidazol; Benzolin; Benzylimidazoline; Divascol; Imidalin; Imidaline; Kasimid;Lambril; Olitensol; Peripherine; Phenylmethylimidazoline; Prefaxil; Pridazole; Priscol; Priscoline; Tolazolin; Tolazolina; Tolazolinum; Vasimid; Vasodil; Vasodilatan; Dilatol ASI; Tolazine [veterinary]; Tolazoline Monohydrochloride; Ciba 3259; Benzolin (VAN); Benzolin (vasodilator); Tolazine [veterinary] (TN); Tolazolina [INN-Spanish]; Tolazoline (INN); Tolazoline [INN:BAN]; Tolazolinum [INN-Latin]; Benzolin (vasodilator) (VAN); 1H-Imidazole, 4,5-dihydro-2-(phenylmethyl)-(9CI); 2-(phenylmethyl)-4,5-dihydro-1H-imidazole; 2-BENZYL-4,5-IMIDAZOLINE HCl; 2-Benzyl-2-imidazoline; 2-Benzyl-4,5-dihydro-1H-imidazole; 2-Benzyl-4,5-imidazoline; 2-Benzylimidazoline; 4,5-Dihydro-2-(phenylmethyl)-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Pulmonary hypertension [ICD-11: BB01; ICD-10: I27, I27.0] | Approved | [1], [2], [3] | |
| Therapeutic Class |
Vasodilator Agents
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| Structure |
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Download2D MOL |
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| Formula |
C10H12N2
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| Canonical SMILES |
C1CN=C(N1)CC2=CC=CC=C2
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| InChI |
1S/C10H12N2/c1-2-4-9(5-3-1)8-10-11-6-7-12-10/h1-5H,6-8H2,(H,11,12)
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| InChIKey |
JIVZKJJQOZQXQB-UHFFFAOYSA-N
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| CAS Number |
CAS 59-98-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9356, 92381, 608291, 5657916, 8153384, 10529062, 11112156, 11335503, 11360742, 11363625, 11366187, 11368749, 11371668, 11373932, 11376911, 11461714, 11466088, 11467208, 11484724, 11485876, 11489020, 11490410, 11492172, 11494545, 15146988, 24857660, 28418847, 29214781, 29224547, 46505641, 47440163, 47515229, 47588908, 47736383, 47885316, 48035019, 48334401, 48416642, 49698326, 49980604, 50100379, 50100380, 50711245, 51072562, 57322812, 85209661, 85787924, 96025298, 103203764, 103936644
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| ChEBI ID |
CHEBI:28502
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| ADReCS Drug ID | BADD_D02239 | |||
| SuperDrug ATC ID |
C04AB02; M02AX02
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| SuperDrug CAS ID |
cas=000059983
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7310). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 006403. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Comparative effects of tolazoline and nitroprusside on human isolated radial artery. Ann Thorac Surg. 2006 Jan;81(1):125-31. | |||
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