Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03OZD
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| Former ID |
DIB018111
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| Drug Name |
(S)-crizotinib
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| Synonyms |
ent-crizotinib
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C21H22Cl2FN5O
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| Canonical SMILES |
CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=C(N=CC(=C2)C3=CN(N=C3)C4CCNCC4)N
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| InChI |
1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m0/s1
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| InChIKey |
KTEIFNKAUNYNJU-LBPRGKRZSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:77555
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy. Nature. 2014 Apr 10;508(7495):222-7. | |||
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