Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03NPH
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| Former ID |
DAP000690
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| Drug Name |
Quazepam
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| Synonyms |
Cetrane; Doral; Dormalin; Oniria; Prosedar; Quazapam; Quazepamum; Quazium; Selepam; Sch 16134; Doral (TN); Dormalin (TN); Quazepamum [INN-Latin]; Sch-161; Sch-16134; Quazepam (JAN/USP); Quazepam [USAN:BAN:INN]; Quazepam (JAN/USP/INN); 7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione; 7-Chloro-5-(o-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-2H-1,4-benzodiazepine-2-thione; 7-chloro-5-(2-fluorophenyl)-1-(2,2,2-trifluoroethyl)-3H-1,4-benzodiazepine-2-thione
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| Drug Type |
Small molecular drug
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| Indication | Insomnia [ICD-11: 7A00-7A0Z] | Approved | [1], [2] | |
| Therapeutic Class |
Hypnotics and Sedatives
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| Company |
Schering-Plough
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| Structure |
 |
Download2D MOL |
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| Formula |
C17H11ClF4N2S
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| Canonical SMILES |
C1C(=S)N(C2=C(C=C(C=C2)Cl)C(=N1)C3=CC=CC=C3F)CC(F)(F)F
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| InChI |
1S/C17H11ClF4N2S/c18-10-5-6-14-12(7-10)16(11-3-1-2-4-13(11)19)23-8-15(25)24(14)9-17(20,21)22/h1-7H,8-9H2
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| InChIKey |
IKMPWMZBZSAONZ-UHFFFAOYSA-N
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| CAS Number |
CAS 36735-22-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9543, 454761, 5183363, 7847523, 7980443, 8153079, 12012678, 14829730, 29224072, 46505952, 49884069, 57322562, 58108231, 80003286, 103770455, 104307989, 128181117, 134222052, 134337979, 134999994, 137005122, 142426129, 160964827, 162946639, 175266458, 178103862, 179150392, 223440821, 226416562, 250127834
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| ChEBI ID |
CHEBI:8694
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| ADReCS Drug ID | BADD_D01887 | |||
| SuperDrug ATC ID |
N05CD10
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| SuperDrug CAS ID |
cas=036735225
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Translocator protein (TSPO) | Target Info | Modulator | [3] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| HTLV-I infection | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7288). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 018708. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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