Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03LNF
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| Former ID |
DIB020687
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| Drug Name |
PFI-1
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| Synonyms |
QCR-192; HY-16586; PF-6405761
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C16H17N3O4S
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| Canonical SMILES |
CN1CC2=C(C=CC(=C2)NS(=O)(=O)C3=CC=CC=C3OC)NC1=O
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| InChI |
1S/C16H17N3O4S/c1-19-10-11-9-12(7-8-13(11)17-16(19)20)18-24(21,22)15-6-4-3-5-14(15)23-2/h3-9,18H,10H2,1-2H3,(H,17,20)
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| InChIKey |
TXZPMHLMPKIUGK-UHFFFAOYSA-N
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| CAS Number |
CAS 1403764-72-6
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:95079
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bromodomain-containing protein 4 (BRD4) | Target Info | Inhibitor | [1] |
| WikiPathways | Chemical Compounds to monitor Proteins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Identification of a chemical probe for bromo and extra C-terminal bromodomain inhibition through optimization of a fragment-derived hit. J Med Chem. 2012 Nov 26;55(22):9831-7. | |||
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