Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03LLM
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| Former ID |
DIB020959
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| Drug Name |
SLG
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| Synonyms |
1-stearoyl-2-linoleoyl-sn-glycerol
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C39H72O5
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| Canonical SMILES |
CCCCCCCCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCC=CCC=CCCCCC
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| InChI |
1S/C39H72O5/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-38(41)43-36-37(35-40)44-39(42)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h12,14,18,20,37,40H,3-11,13,15-17,19,21-36H2,1-2H3/b14-12-,20-18-/t37-/m0/s1
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| InChIKey |
AJMZUFBKADIAKC-SKTOPKGQSA-N
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| CAS Number |
CAS 34487-26-8
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:77097
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Short transient receptor potential channel 6 (TRPC6) | Target Info | Activator | [2] |
| Panther Pathway | Alzheimer disease-presenilin pathway | |||
| Pathway Interaction Database | Endothelins | |||
| Nephrin/Neph1 signaling in the kidney podocyte | ||||
| EPO signaling pathway | ||||
| PAR1-mediated thrombin signaling events | ||||
| Reactome | Effects of PIP2 hydrolysis | |||
| TRP channels | ||||
| Role of second messengers in netrin-1 signaling | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| Platelet homeostasis | ||||
| Netrin-1 signaling | ||||
| GPCR downstream signaling | ||||
| Effects of PIP2 hydrolysis | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2442). | |||
| REF 2 | Direct activation of human TRPC6 and TRPC3 channels by diacylglycerol. Nature. 1999 Jan 21;397(6716):259-63. | |||
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