Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03LGY
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| Former ID |
DAP000556
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| Drug Name |
Divalproex sodium
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| Synonyms |
Delepsine; Depakote; Divalproate; Divalproex; Epilex; Epival; Sprinkle; Valcote; Valdisoval; Valparin; Depakote CP; Depakote ER; Depakote Sprinkle; Divalproex sodium [USAN]; Sodium divalproate; Sodium hydrogen divalproate; Valproate semisodique; Valproate semisodique [French]; Valproate semisodium; Valproato semisodico; Valproato semisodico [Spanish]; Valproatum seminatricum; Valproatum seminatricum [Latin]; Abbott 50711; Abbott-50711; Depacon (TN); Depakote (TN); Depakote ER (TN); Divalproex sodium (USP); Epival (TN); Ergenyl Chrono (TN); Valance (TN); Valproate semisodium (INN); Divalproex sodium, Depakote, Epival; Natrium hydrogen bis(2-propylvalerat); Sodium hydrogen bis(2-propylpentanoate); Sodium hydrogen bis(2-propylvalerate); Valproic acid semisodium salt (2:1); Zalkote. (TN); Sodium hydrogen bis(2-propylvalerate), oligomer; Sodium 2-propylpentanoate-2-propylpentanoic acid (1:1); Pentanoic acid, 2-propyl-, sodium salt (2:1); Pentanoic acid, 2-propyl-, sodium salt(2:1); 2-propylpentanoate
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| Drug Type |
Small molecular drug
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| Indication | Seizure disorder [ICD-11: 8A6Z; ICD-9: 345.9, 780.3] | Approved | [1] | |
| Therapeutic Class |
Anticonvulsants
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| Company |
Abbott Laboratories
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H31NaO4
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| Canonical SMILES |
CCCC(CCC)C(=O)O.CCCC(CCC)C(=O)[O-].[Na+]
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| InChI |
1S/2C8H16O2.Na/c2*1-3-5-7(6-4-2)8(9)10;/h2*7H,3-6H2,1-2H3,(H,9,10);/q;;+1/p-1
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| InChIKey |
MSRILKIQRXUYCT-UHFFFAOYSA-M
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| CAS Number |
CAS 76584-70-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7847370, 12013303, 16653561, 34717600, 46507273, 50002863, 56039245, 57386929, 80601215, 81043871, 99319094, 104253321, 117375017, 117375779, 124757440, 125164244, 125357399, 126659517, 126665937, 131325899, 134337847, 135010881, 135692234, 137002488, 152034619, 160708725, 160963855, 162186565, 164809345, 179235957, 184545727, 223681007, 224479010, 226426116, 241136581, 251915945, 251917293, 252219977, 252348612
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| ChEBI ID |
CHEBI:4667
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| ADReCS Drug ID | BADD_D00696 ; BADD_D02329 | |||
| SuperDrug ATC ID |
N03AG01
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transaminase (ABAT) | Target Info | Inhibitor | [2] |
| BioCyc | GABA shunt | |||
| Valine degradation | ||||
| Beta-alanine degradation | ||||
| 4-aminobutyrate degradation | ||||
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Valine, leucine and isoleucine degradation | ||||
| beta-Alanine metabolism | ||||
| Propanoate metabolism | ||||
| Butanoate metabolism | ||||
| Metabolic pathways | ||||
| GABAergic synapse | ||||
| Panther Pathway | Aminobutyrate degradation | |||
| Pyrimidine Metabolism | ||||
| Gamma-aminobutyric acid synthesis | ||||
| Pathwhiz Pathway | Aspartate Metabolism | |||
| Glutamate Metabolism | ||||
| Beta-Alanine Metabolism | ||||
| Valine, Leucine and Isoleucine Degradation | ||||
| Propanoate Metabolism | ||||
| WikiPathways | GABA synthesis, release, reuptake and degradation | |||
| Alanine and aspartate metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | FDA approved drugs (1996) in CenterWatch | |||
| REF 2 | DrugBank: a knowledgebase for drugs, drug actions and drug targets. Nucleic Acids Res. 2008 Jan;36(Database issue):D901-6. | |||
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