Drug Information
Drug General Information | Top | |||
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Drug ID |
D03IMY
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Former ID |
DNC007875
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Drug Name |
6-chloro-5-heptylpyrimidine-2,4(1H,3H)-dione
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Synonyms |
CHEMBL435558; BDBM20059; 5-Substituted-6-chlorouracil, 5f
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C11H17ClN2O2
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Canonical SMILES |
CCCCCCCC1=C(NC(=O)NC1=O)Cl
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InChI |
1S/C11H17ClN2O2/c1-2-3-4-5-6-7-8-9(12)13-11(16)14-10(8)15/h2-7H2,1H3,(H2,13,14,15,16)
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InChIKey |
CIAJCIKDDKGJBP-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Thymidine phosphorylase (TYMP) | Target Info | Inhibitor | [1] |
BioCyc | Pyrimidine deoxyribonucleosides degradation | |||
KEGG Pathway | Pyrimidine metabolism | |||
Drug metabolism - other enzymes | ||||
Metabolic pathways | ||||
Bladder cancer | ||||
NetPath Pathway | TSH Signaling Pathway | |||
Pathwhiz Pathway | Pyrimidine Metabolism | |||
WikiPathways | Bladder Cancer | |||
Metabolism of nucleotides | ||||
Fluoropyrimidine Activity |
References | Top | |||
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REF 1 | Discovery of 5-substituted-6-chlorouracils as efficient inhibitors of human thymidine phosphorylase. J Med Chem. 2007 Nov 29;50(24):6016-23. |
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