Drug Information
Drug General Information | Top | |||
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Drug ID |
D03IDX
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Drug Name |
WA-8242-A1
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Synonyms |
171272-08-5; 204272-98-0; 204273-00-7; WA-8242-A2; WA-8242-B
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1], [2] |
Target and Pathway | Top | |||
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Target(s) | Phospholipase A2 (PLA2G1B) | Target Info | Modulator | [1], [2] |
BioCyc | Phospholipases | |||
KEGG Pathway | Glycerophospholipid metabolism | |||
Ether lipid metabolism | ||||
Arachidonic acid metabolism | ||||
Linoleic acid metabolism | ||||
alpha-Linolenic acid metabolism | ||||
Metabolic pathways | ||||
Ras signaling pathway | ||||
Vascular smooth muscle contraction | ||||
Pancreatic secretion | ||||
Fat digestion and absorption | ||||
Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
Reactome | Acyl chain remodelling of PC | |||
Acyl chain remodelling of PE | ||||
Acyl chain remodelling of PI | ||||
WikiPathways | Glycerophospholipid biosynthesis |
References | Top | |||
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REF 1 | WA8242A1, A2 and B, novel secretary phospholipase A2 inhibitors produced by Streptomyces violaceusniger. III. Structure elucidation and total synth... J Antibiot (Tokyo). 1998 Jul;51(7):655-64. | |||
REF 2 | WA8242A1, A2 and B, novel secretory phospholipase A2 inhibitors produced by Streptomyces violaceusniger. I. Taxonomy, production and purification. J Antibiot (Tokyo). 1998 Jan;51(1):1-7. |
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