Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03FJK
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| Former ID |
DNC005065
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| Drug Name |
8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine
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| Synonyms |
CHEMBL183159; 8-(1,3,3-Trimethyl-butoxy)-quinolin-2-ylamine; SCHEMBL5884151; ZDVPLVAZUCNXKZ-UHFFFAOYSA-N; BDBM50152425
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H22N2O
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| Canonical SMILES |
CC(CC(C)(C)C)OC1=CC=CC2=C1N=C(C=C2)N
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| InChI |
1S/C16H22N2O/c1-11(10-16(2,3)4)19-13-7-5-6-12-8-9-14(17)18-15(12)13/h5-9,11H,10H2,1-4H3,(H2,17,18)
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| InChIKey |
ZDVPLVAZUCNXKZ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Melanin-concentrating hormone receptor 1 (MCHR1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Peptide ligand-binding receptors | |||
| G alpha (q) signalling events | ||||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 2. Bioorg Med Chem Lett. 2004 Oct 4;14(19):4879-82. | |||
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