Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03DHQ
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| Former ID |
DCL000760
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| Drug Name |
CX-516
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| Synonyms |
Ampalex; BDP 12; CX 516; CX516; BDP-12; SPD-420; Piperidin-1-yl(quinoxalin-6-yl)methanone; 1-(6-Quinoxalinylcarbonyl)piperidine; 1-(6-quinoxalinylcarbonyl)-Piperidine; 1-(quinoxalin-6-ylcarbonyl)piperidine; 6-(piperidin-1-ylcarbonyl)quinoxaline
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| Drug Type |
Small molecular drug
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| Indication | Pervasive developmental disorder [ICD-11: 6A00-6A0Z] | Phase 2/3 | [1], [2] | |
| Schizophrenia [ICD-11: 6A20] | Phase 2/3 | [1], [2] | ||
| Company |
Cortex
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| Structure |
 |
Download2D MOL |
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| Formula |
C14H15N3O
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| Canonical SMILES |
C1CCN(CC1)C(=O)C2=CC3=NC=CN=C3C=C2
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| InChI |
1S/C14H15N3O/c18-14(17-8-2-1-3-9-17)11-4-5-12-13(10-11)16-7-6-15-12/h4-7,10H,1-3,8-9H2
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| InChIKey |
ANDGGVOPIJEHOF-UHFFFAOYSA-N
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| CAS Number |
CAS 154235-83-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
586267, 10249834, 14823193, 46225133, 50014454, 50407829, 57346716, 58107168, 87245449, 92719586, 93309743, 93581252, 96021227, 99300590, 99431536, 99437665, 99452656, 103374311, 103991908, 104418433, 118845667, 123046084, 125341848, 126574412, 126628160, 126651821, 126671254, 126733033, 127430856, 134339248, 135105380, 136377903, 136946430, 137008005, 142542261, 143493398, 144115603, 145238952, 152213031, 152242353, 160815141, 162190884, 162221093, 163090027, 163620727, 163686041, 163801192, 164045281, 164187479, 164831044
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| ChEBI ID |
CHEBI:34605
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| SuperDrug ATC ID |
P01BB02
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| SuperDrug CAS ID |
cas=000609789
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4165). | |||
| REF 2 | Autism spectrum disorders: emerging pharmacotherapy. Expert Opin Emerg Drugs. 2005 Aug;10(3):521-36. | |||
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