Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03BXU
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| Former ID |
DNCL001962
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| Drug Name |
LNK-754
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| Synonyms |
LNK 754; 439153-64-7; LNK-754; OSI 754; CP 609754; CP-609,754; DTXSID60195986; 2(1H)-Quinolinone, 6-((4-chlorophenyl)hydroxy(1-methyl-1H-imidazol-5-yl)methyl)-4-(3-ethynylphenyl)-1-methyl-
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| Drug Type |
Small molecular drug
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| Indication | Bladder cancer [ICD-11: 2C94; ICD-9: 188] | Phase 1 | [1] | |
| Company |
Link Medicine
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| Structure |
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Download2D MOL |
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| Formula |
C29H22ClN3O2
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| Canonical SMILES |
CN1C=NC=C1C(C2=CC=C(C=C2)Cl)(C3=CC4=C(C=C3)N(C(=O)C=C4C5=CC=CC(=C5)C#C)C)O
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| InChI |
1S/C29H22ClN3O2/c1-4-19-6-5-7-20(14-19)24-16-28(34)33(3)26-13-10-22(15-25(24)26)29(35,27-17-31-18-32(27)2)21-8-11-23(30)12-9-21/h1,5-18,35H,2-3H3/t29-/m1/s1
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| InChIKey |
JAHDAIPFBPPQHQ-GDLZYMKVSA-N
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| CAS Number |
CAS 1190094-64-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A phase I open label study of the farnesyltransferase inhibitor CP-609,754 in patients with advanced malignant tumors. Clin Cancer Res. 2004 Nov 1;10(21):7127-35. | |||
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