Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D03BSR
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| Former ID |
DIB020555
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| Drug Name |
NNC55-0396
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| Synonyms |
NNC 55-0396
Click to Show/Hide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C30H38FN3O2
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| Canonical SMILES |
CC(C)C1C2=C(CCC1(CCN(C)CCCC3=NC4=CC=CC=C4N3)OC(=O)C5CC5)C=C(C=C2)F
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| InChI |
1S/C30H38FN3O2/c1-20(2)28-24-13-12-23(31)19-22(24)14-15-30(28,36-29(35)21-10-11-21)16-18-34(3)17-6-9-27-32-25-7-4-5-8-26(25)33-27/h4-5,7-8,12-13,19-21,28H,6,9-11,14-18H2,1-3H3,(H,32,33)/t28-,30-/m0/s1
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| InChIKey |
VHHVPDKNKPNKHY-JDXGNMNLSA-N
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| CAS Number |
CAS 357400-14-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| ChEBI ID |
CHEBI:93374
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cation channel sperm-associated protein (CatSper) | Target Info | Blocker (channel blocker) | [2] |
| Cation channel sperm-associated protein 1 (CatSper1) | Target Info | Blocker (channel blocker) | [2] | |
| Cation channel sperm-associated protein 2 (CatSper2) | Target Info | Blocker (channel blocker) | [2] | |
| Cation channel sperm-associated protein 3 (CatSper3) | Target Info | Blocker (channel blocker) | [2] | |
| WikiPathways | Fertilization | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4269). | |||
| REF 2 | The CatSper channel mediates progesterone-induced Ca2+ influx in human sperm. Nature. 2011 Mar 17;471(7338):382-6. | |||
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