Drug Information
Drug General Information | Top | |||
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Drug ID |
D03BAB
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Former ID |
DNC008860
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Drug Name |
Cacospongionolide E
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Synonyms |
cacospongionolide E; CHEMBL480874; BDBM50259952
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C25H36O4
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Canonical SMILES |
CC1CCC2(C(C1(C)CCC3=CCC(OC3)C4=CC(=O)OC4O)CCC=C2C)C
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InChI |
1S/C25H36O4/c1-16-6-5-7-21-24(16,3)12-10-17(2)25(21,4)13-11-18-8-9-20(28-15-18)19-14-22(26)29-23(19)27/h6,8,14,17,20-21,23,27H,5,7,9-13,15H2,1-4H3/t17-,20+,21-,23+,24-,25-/m0/s1
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InChIKey |
WBDQPITVPUAHAN-DRCQBYJMSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Group IIA phospholipase A2 (GIIA sPLA2) | Target Info | Inhibitor | [1] |
Phospholipase A2 (PLA2G1B) | Target Info | Inhibitor | [1] | |
BioCyc | Phospholipases | |||
KEGG Pathway | Glycerophospholipid metabolism | |||
Ether lipid metabolism | ||||
Arachidonic acid metabolism | ||||
Linoleic acid metabolism | ||||
alpha-Linolenic acid metabolism | ||||
Metabolic pathways | ||||
Ras signaling pathway | ||||
Vascular smooth muscle contraction | ||||
Pancreatic secretion | ||||
Fat digestion and absorption | ||||
Pathway Interaction Database | Glypican 1 network | |||
Fc-epsilon receptor I signaling in mast cells | ||||
Reactome | Acyl chain remodelling of PC | |||
Acyl chain remodelling of PE | ||||
Acyl chain remodelling of PI | ||||
WikiPathways | Cardiac Hypertrophic Response | |||
Glycerophospholipid biosynthesis | ||||
Glycerophospholipid Biosynthetic Pathway | ||||
Spinal Cord Injury | ||||
Eicosanoid Synthesis | ||||
MicroRNAs in cardiomyocyte hypertrophy |
References | Top | |||
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REF 1 | A new cacospongionolide inhibitor of human secretory phospholipase A2 from the Tyrrhenian sponge Fasciospongia cavernosa and absolute configuration... J Nat Prod. 1998 Jul;61(7):931-5. |
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