Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02WWM
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| Former ID |
DIB020288
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| Drug Name |
LY97241
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| Synonyms |
LY 97241; LY-97241
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C19H32N2O2
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| Canonical SMILES |
CCCCCCCN(CC)CCCCC1=CC=C(C=C1)[N+](=O)[O-]
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| InChI |
1S/C19H32N2O2/c1-3-5-6-7-9-16-20(4-2)17-10-8-11-18-12-14-19(15-13-18)21(22)23/h12-15H,3-11,16-17H2,1-2H3
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| InChIKey |
YTYATOMQOOFRNA-UHFFFAOYSA-N
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| CAS Number |
CAS 72456-63-4
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated potassium channel Kv10.1 (KCNH1) | Target Info | Blocker (channel blocker) | [2] |
| Voltage-gated potassium channel Kv10.2 (KCNH5) | Target Info | Blocker (channel blocker) | [3] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2606). | |||
| REF 2 | Inhibition of hEAG1 and hERG1 potassium channels by clofilium and its tertiary analogue LY97241. Br J Pharmacol. 2003 Jan;138(1):161-71. | |||
| REF 3 | Molecular determinants for high-affinity block of human EAG potassium channels by antiarrhythmic agents. Mol Pharmacol. 2004 May;65(5):1120-9. | |||
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