Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02TYC
|
|||
| Former ID |
DNC000309
|
|||
| Drug Name |
BetaARKct
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Beta-adrenergic receptor kinase 1 (ADRBK1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Chemokine signaling pathway | |||
| Endocytosis | ||||
| Glutamatergic synapse | ||||
| Morphine addiction | ||||
| Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
| Parkinson disease | ||||
| Angiotensin II-stimulated signaling through G proteins and beta-arrestin | ||||
| Pathway Interaction Database | Signaling events mediated by HDAC Class II | |||
| Thromboxane A2 receptor signaling | ||||
| CXCR4-mediated signaling events | ||||
| Signaling events mediated by the Hedgehog family | ||||
| IL8- and CXCR1-mediated signaling events | ||||
| Reactome | Calmodulin induced events | |||
| G alpha (q) signalling events | ||||
| Activation of SMO | ||||
| WikiPathways | Hedgehog Signaling Pathway | |||
| DAG and IP3 signaling | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Opioid Signalling | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Gene-mediated inhibition of the b-adrenergic receptor kinase: a new therapeutic strategy for heart failure. Minerva Cardioangiol. 2001 Dec;49(6):389-94. | |||
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