Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02TJT
|
|||
| Former ID |
DNCL003833
|
|||
| Drug Name |
MK-8109
|
|||
| Indication | Ovarian cancer [ICD-11: 2C73; ICD-10: C56] | Phase 3 | [1] | |
| Company |
Merck
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Folate receptor alpha (FOLR1) | Target Info | Modulator | [2] |
| KEGG Pathway | Endocytosis | |||
| Reactome | COPII (Coat Protein 2) Mediated Vesicle Transport | |||
| Cargo concentration in the ER | ||||
| WikiPathways | Folate Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of Endocyte. | |||
| REF 2 | A current review of folate receptor alpha as a potential tumor target in non-small-cell lung cancer. Drug Des Devel Ther. 2015; 9: 4989-4996. | |||
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