Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02RVN
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| Former ID |
DIB010636
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| Drug Name |
Selurampanel
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| Synonyms |
BGG-492; BGG-492A; AMPA antagonist (oral, epilepsy), Novartis
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| Drug Type |
Small molecular drug
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| Indication | Epilepsy [ICD-11: 8A60-8A68] | Phase 2 | [1] | |
| Company |
Novartis pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C16H19N5O4S
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| Canonical SMILES |
CC(C)C1=C(C=C2C(=C1)NC(=O)N(C2=O)NS(=O)(=O)C)C3=CC=NN3C
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| InChI |
1S/C16H19N5O4S/c1-9(2)10-8-13-12(7-11(10)14-5-6-17-20(14)3)15(22)21(16(23)18-13)19-26(4,24)25/h5-9,19H,1-4H3,(H,18,23)
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| InChIKey |
MCECSFFXUPEPDB-UHFFFAOYSA-N
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| CAS Number |
CAS 912574-69-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate receptor AMPA (GRIA) | Target Info | Antagonist | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01302873) Study of BGG492 in Patients With Chronic Subjective Tinnitus. U.S. National Institutes of Health. | |||
| REF 2 | BGG492 (selurampanel), an AMPA/kainate receptor antagonist drug for epilepsy. Expert Opin Investig Drugs. 2014 Jan;23(1):107-13. | |||
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