Drug Information
Drug General Information | Top | |||
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Drug ID |
D02RQT
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Former ID |
DNC014533
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Drug Name |
Tenidap
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Drug Type |
Small molecular drug
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Indication | Rheumatoid arthritis [ICD-11: FA20] | Phase 3 | [1], [2] | |
Structure |
Download2D MOL |
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Formula |
C14H9ClN2O3S
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Canonical SMILES |
C1=CSC(=C1)C(=O)C2=C(N(C3=C2C=C(C=C3)Cl)C(=O)N)O
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InChI |
1S/C14H9ClN2O3S/c15-7-3-4-9-8(6-7)11(13(19)17(9)14(16)20)12(18)10-2-1-5-21-10/h1-6,19H,(H2,16,20)
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InChIKey |
IZSFDUMVCVVWKW-UHFFFAOYSA-N
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CAS Number |
CAS 120210-48-2
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PubChem Compound ID | ||||
PubChem Substance ID |
7980752, 14718345, 14874738, 26683989, 26686056, 29216033, 31919866, 47207730, 50064246, 53789318, 88531322, 104829165, 135028984, 135651243, 135698204, 137231438, 143388439, 160671983, 164150758, 164814894, 172914502, 179149455, 179294229, 198938260, 198993721, 204359548, 226413131, 227840142, 252156629, 252356965
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ChEBI ID |
CHEBI:35847
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SuperDrug ATC ID |
M01AX23
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Target and Pathway | Top | |||
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Target(s) | Arachidonate 5-lipoxygenase (5-LOX) | Target Info | Modulator | [2] |
BioCyc | Aspirin-triggered lipoxin biosynthesis | |||
Resolvin D biosynthesis | ||||
Leukotriene biosynthesis | ||||
Lipoxin biosynthesis | ||||
Aspirin triggered resolvin D biosynthesis | ||||
Aspirin triggered resolvin E biosynthesis | ||||
KEGG Pathway | Arachidonic acid metabolism | |||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Ovarian steroidogenesis | ||||
Toxoplasmosis | ||||
NetPath Pathway | IL4 Signaling Pathway | |||
Pathwhiz Pathway | Arachidonic Acid Metabolism | |||
WikiPathways | Vitamin D Receptor Pathway | |||
Arachidonic acid metabolism | ||||
Eicosanoid Synthesis | ||||
Selenium Micronutrient Network |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2395). | |||
REF 2 | The in vitro free radical scavenging activity of tenidap, a new dual cyclo-oxygenase and 5-1ipoxygenase inhibitor. Mediators Inflamm. 1992;1(2):141-3. |
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