Drug Information
Drug General Information | Top | |||
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Drug ID |
D02PKR
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Former ID |
DNC012134
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Drug Name |
3-Bromo-6-nitro-2-piperazin-1-yl-quinoline
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Synonyms |
CHEMBL290523; 3-bromo-6-nitro-2-piperazin-1-yl-quinoline; SCHEMBL6365221; MPHPQAKQQDLIGK-UHFFFAOYSA-N; BDBM50090214; 2-Piperazino-3-bromo-6-nitroquinoline
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H13BrN4O2
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Canonical SMILES |
C1CN(CCN1)C2=C(C=C3C=C(C=CC3=N2)[N+](=O)[O-])Br
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InChI |
1S/C13H13BrN4O2/c14-11-8-9-7-10(18(19)20)1-2-12(9)16-13(11)17-5-3-15-4-6-17/h1-2,7-8,15H,3-6H2
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InChIKey |
MPHPQAKQQDLIGK-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Serotonin transporter (SERT) | Target Info | Inhibitor | [1] |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
WikiPathways | Monoamine Transport | |||
SIDS Susceptibility Pathways | ||||
NRF2 pathway | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity |
References | Top | |||
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REF 1 | Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 1. Bioorg Med Chem Lett. 2000 Jul 17;10(14):1559-62. |
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