Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02KVR
|
|||
| Former ID |
DIB020193
|
|||
| Drug Name |
LB42708
|
|||
| Synonyms |
LB42708; 226929-39-1; LB 42708; C30H27BrN4O2; SCHEMBL6975755; GTPL8029; AOB5942; MolPort-023-277-136; HMS3653F07; BCP09683; ZINC1490366; EX-A2090; s7467; 2507AH; AKOS024458079; SB19586; NCGC00370772-05; LB-42708; BC600547; SW220047-1; FT-0720438; 4-[[1-[[1-[(4-Bromophenyl)methyl]-1H-imidazol-5-yl]methyl]-4-(1-naphthalenyl)-1H-pyrrol-3-yl]carbonyl]morpholine; 4-[1-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-4-(naphthalen-1-yl)-1H-pyrrole-3-carbonyl]morpholine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
|
||
| Formula |
C30H27BrN4O2
|
|||
| Canonical SMILES |
C1COCCN1C(=O)C2=CN(C=C2C3=CC=CC4=CC=CC=C43)CC5=CN=CN5CC6=CC=C(C=C6)Br
|
|||
| InChI |
1S/C30H27BrN4O2/c31-24-10-8-22(9-11-24)17-35-21-32-16-25(35)18-33-19-28(27-7-3-5-23-4-1-2-6-26(23)27)29(20-33)30(36)34-12-14-37-15-13-34/h1-11,16,19-21H,12-15,17-18H2
|
|||
| InChIKey |
GUUIRIMAQGOLHT-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The farnesyltransferase inhibitor LB42708 suppresses vascular endothelial growth factor-induced angiogenesis by inhibiting ras-dependent mitogen-activated protein kinase and phosphatidylinositol 3-kinase/Akt signal pathways. Mol Pharmacol. 2010 Jul;78(1):142-50. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.