Drug Information
Drug General Information | Top | |||
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Drug ID |
D02KMO
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Former ID |
DAP001417
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Drug Name |
Pinacidil
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Synonyms |
Pinacidilum; P 1134; S 1230; P-154; Pinacidil (anhydrous); Pinacidilum [INN-Latin]; S-1230; N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)guanidine; Guanidine, 2-cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)-, monohydrate; Guanidine, N-cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-, monohydrate; (+-)-Pinacidil; (+/-)-N-Cyano-N'-4-pyridinyl-N"-(1,2,2-trimethylpropyl)guanidine; (R,S)-Pinacidil; (inverted question mark)-N-Cyano-N'-4-pyridinyl-N''-(1,2,2-trimethylpropyl)-guanidine; 1-cyano-2-(3,3-dimethylbutan-2-yl)-3-pyridin-4-ylguanidine; 2-Cyano-3-(4-pyridinyl)-1-(1,2,2-trimethylpropyl)guanidine; 2-Cyano-3-(4-pyridyl)-1-(1,2,2-trimethylpropyl)guanidine monohydrate
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Drug Type |
Small molecular drug
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Indication | High blood pressure [ICD-11: BA00; ICD-10: I10; ICD-9: 401] | Approved | [1], [2] | |
Therapeutic Class |
Antihypertensive Agents
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Structure |
Download2D MOL |
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Formula |
C13H19N5
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Canonical SMILES |
CC(C(C)(C)C)N=C(NC#N)NC1=CC=NC=C1
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InChI |
1S/C13H19N5/c1-10(13(2,3)4)17-12(16-9-14)18-11-5-7-15-8-6-11/h5-8,10H,1-4H3,(H2,15,16,17,18)
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InChIKey |
IVVNZDGDKPTYHK-UHFFFAOYSA-N
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CAS Number |
CAS 60560-33-0
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PubChem Compound ID | ||||
PubChem Substance ID |
4669683, 8152962, 10321422, 11120045, 11120533, 11121021, 11121526, 11122006, 11147128, 11342030, 11362213, 11362595, 11363281, 11365157, 11365843, 11367719, 11368405, 11370461, 11370462, 11373320, 11375881, 11376567, 11466274, 11467394, 11485554, 11485987, 11487615, 11489555, 11494201, 11532877, 14892701, 15196571, 17405595, 24277866, 26613193, 26679753, 26749106, 26749107, 26752205, 26752206, 29223908, 47425317, 47721339, 47721634, 47944819, 47944820, 48019685, 48020021, 48170469, 48244097
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ChEBI ID |
CHEBI:91706
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SuperDrug ATC ID |
C02DG01
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SuperDrug CAS ID |
cas=085371648
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Target and Pathway | Top | |||
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Target(s) | Potassium channel unspecific (KC) | Target Info | Modulator | [3] |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2412). | |||
REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 019456. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. |
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