Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02JUP
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| Former ID |
DNC002878
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| Drug Name |
5'-Deoxy-5'-(Methylthio)-Tubercidin
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| Synonyms |
5'-methylthiotubercidin; 5'-DEOXY-5'-(METHYLTHIO)-TUBERCIDIN; 2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-METHYLSULFANYLMETHYL-TETRAHYDRO-FURAN-3,4-DIOL; MTH; 2qtg; 7-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-7H-pyrrolo(2,3-d)pyrimidin-4-amine; 7-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine; 61893-98-9; 1nc1; AC1Q7DT3; AC1L4MN1; 5'-(methylsulfanyl)tubercidin; CHEMBL551561; DB02933; 7-(5-s-methyl-5-thio-; A-d-ribofuranosyl)-7h-pyrrolo[2,3-d]pyrimidin-4-amine; 7H-Pyrrolo(2,3-d)pyrimidin-4-amine,
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H16N4O3S
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| Canonical SMILES |
CSCC1C(C(C(O1)N2C=CC3=C(N=CN=C32)N)O)O
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| InChI |
1S/C12H16N4O3S/c1-20-4-7-8(17)9(18)12(19-7)16-3-2-6-10(13)14-5-15-11(6)16/h2-3,5,7-9,12,17-18H,4H2,1H3,(H2,13,14,15)/t7-,8-,9-,12-/m1/s1
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| InChIKey |
WBPLMFVTQMIPLW-MFYTUXHUSA-N
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| CAS Number |
CAS 61893-98-9
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial MTA/SAH nucleosidase (Bact mtnN) | Target Info | Inhibitor | [1] |
| S-methyl-5'-thioadenosine phosphorylase (MTAP) | Target Info | Inhibitor | [1] | |
| BioCyc | S-methyl-5'-thioadenosine degradation | |||
| Methionine salvage cycle III | ||||
| KEGG Pathway | Cysteine and methionine metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Methionine Metabolism | |||
| WikiPathways | Metabolism of amino acids and derivatives | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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