Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02IRL
|
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| Former ID |
DCL000539
|
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| Drug Name |
IDX375
|
|||
| Indication | Hepatitis C virus infection [ICD-11: 1E51.1; ICD-10: B18.2] | Discontinued in Phase 2 | [1] | |
| Company |
Idenix
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C24H37N4O6PS
|
|||
| Canonical SMILES |
CCOP1(=O)C2=C(C=CC(=C2)NS(=O)(=O)C)NC(=N1)C3=C(C(N(C3=O)CCC(C)(C)C)C(C)(C)C)O
|
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| InChI |
1S/C24H37N4O6PS/c1-9-34-35(31)17-14-15(27-36(8,32)33)10-11-16(17)25-21(26-35)18-19(29)20(24(5,6)7)28(22(18)30)13-12-23(2,3)4/h10-11,14,20,27,29H,9,12-13H2,1-8H3,(H,25,26,31)/t20-,35+/m1/s1
|
|||
| InChIKey |
FKLYVKZFUGOUQH-GOKJBEJGSA-N
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hepatitis C virus RNA-directed RNA polymerase (HCV NS5B) | Target Info | Inhibitor | [2], [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800031314) | |||
| REF 2 | Therapy with amineptine, a dopamine reuptake inhibitor, in patients with major depression. Indian J Psychiatry. 1997 Apr;39(2):147-53. | |||
| REF 3 | Clinical pipeline report, company report or official report of Idenix (2009). | |||
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