Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02HEK
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| Former ID |
DNC011526
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| Drug Name |
1-(9H-beta-Carbolin-3-yl)-ethanone
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| Synonyms |
82596-93-8; 3-acetyl-beta-carboline; 1-(9H-pyrido[3,4-b]indol-3-yl)-ethanone; CHEMBL11863; SCHEMBL10857122; CTK3D8180; DTXSID90509895; MPLXFBXMWYMAFN-UHFFFAOYSA-N; ZINC26025316; AKOS030597437; 1-(9H-beta-Carbolin-3-yl)ethan-1-one; Ethanone, 1-(9H-pyrido[3,4-b]indol-3-yl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H10N2O
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| Canonical SMILES |
CC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
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| InChI |
1S/C13H10N2O/c1-8(16)12-6-10-9-4-2-3-5-11(9)15-13(10)7-14-12/h2-7,15H,1H3
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| InChIKey |
MPLXFBXMWYMAFN-UHFFFAOYSA-N
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| CAS Number |
CAS 82596-93-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Iron uptake and transport | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists. J Med Chem. 1987 Apr;30(4):750-3. | |||
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