Drug Information
Drug General Information | Top | |||
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Drug ID |
D02GSL
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Former ID |
DNC011417
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Drug Name |
4-Iodo-6-nitro-2-piperazin-1-yl-quinoline
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Synonyms |
CHEMBL167475; 4-Iodo-6-nitro-2-piperazin-1-yl-quinoline; SCHEMBL6365240; BDBM50110579
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C13H13IN4O2
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Canonical SMILES |
C1CN(CCN1)C2=NC3=C(C=C(C=C3)[N+](=O)[O-])C(=C2)I
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InChI |
1S/C13H13IN4O2/c14-11-8-13(17-5-3-15-4-6-17)16-12-2-1-9(18(19)20)7-10(11)12/h1-2,7-8,15H,3-6H2
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InChIKey |
ABNBXDNNSDJWKN-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Serotonin transporter (SERT) | Target Info | Inhibitor | [1] |
KEGG Pathway | Serotonergic synapse | |||
NetPath Pathway | TCR Signaling Pathway | |||
Panther Pathway | 5HT1 type receptor mediated signaling pathway | |||
5HT2 type receptor mediated signaling pathway | ||||
5HT3 type receptor mediated signaling pathway | ||||
5HT4 type receptor mediated signaling pathway | ||||
WikiPathways | Monoamine Transport | |||
SIDS Susceptibility Pathways | ||||
NRF2 pathway | ||||
Synaptic Vesicle Pathway | ||||
Serotonin Transporter Activity |
References | Top | |||
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REF 1 | Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 2: 4-substituted 6-nitroquipazines. Bioorg Med Chem Lett. 2002 Mar 11;12(5):811-5. |
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