Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02GNL
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| Former ID |
DIB003088
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| Drug Name |
KMJ-372
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| Synonyms |
MK-271; TRPV1 antagonists (pain), Digital Biotech/Grunenthal; TRPV1 antagonists (pain), Medifron/Grunenthal; VR1 antagonists (pain), Digital Biotech/Grunenthal; Vanilloid antagonists (analgesic), Digital Biotech/Grunenthal; (S)-KMJ-372
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| Indication | Pain [ICD-11: MG30-MG3Z] | Investigative | [1] | |
| Company |
Digital Biotech Co Ltd
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| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Transient receptor potential cation channel V1 (TRPV1) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Inflammatory mediator regulation of TRP channels | ||||
| NetPath Pathway | IL2 Signaling Pathway | |||
| Pathway Interaction Database | Trk receptor signaling mediated by the MAPK pathway | |||
| Trk receptor signaling mediated by PI3K and PLC-gamma | ||||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 507). | |||
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