Drug Information
Drug General Information | Top | |||
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Drug ID |
D02FCY
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Former ID |
DIB020479
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Drug Name |
NAAG
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Synonyms |
N-acetylaspartylglutamate; spaglumic acid; isospaglumic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C11H16N2O8
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Canonical SMILES |
CC(=O)NC(CC(=O)O)C(=O)NC(CCC(=O)O)C(=O)O
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InChI |
1S/C11H16N2O8/c1-5(14)12-7(4-9(17)18)10(19)13-6(11(20)21)2-3-8(15)16/h6-7H,2-4H2,1H3,(H,12,14)(H,13,19)(H,15,16)(H,17,18)(H,20,21)/t6-,7-/m0/s1
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InChIKey |
OPVPGKGADVGKTG-BQBZGAKWSA-N
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CAS Number |
CAS 3106-85-2
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PubChem Compound ID | ||||
PubChem Substance ID |
7980673, 8150014, 10669851, 11112559, 11113480, 11335837, 11361076, 11363293, 11365855, 11368417, 11371698, 11374703, 11376579, 11462048, 11467119, 11468239, 11485238, 11486787, 11489387, 11490575, 11492688, 11494213, 11537717, 14825413, 26612503, 26680122, 26751698, 33510452, 47216778, 47216779, 47736484, 47810759, 47959745, 76680351, 85182292, 91011602, 92126028, 99301750, 103913863, 104171316, 113444559, 124636732, 124882459, 128844339, 135651520, 136930122, 142202893, 144075620, 162222804, 164174696
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ChEBI ID |
CHEBI:73688
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Target and Pathway | Top | |||
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Target(s) | Metabotropic glutamate receptor 3 (mGluR3) | Target Info | Agonist | [2] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Glutamatergic synapse | ||||
Cocaine addiction | ||||
Panther Pathway | Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | |||
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | ||||
Ionotropic glutamate receptor pathway | ||||
Metabotropic glutamate receptor group II pathway | ||||
Reactome | G alpha (i) signalling events | |||
Class C/3 (Metabotropic glutamate/pheromone receptors) | ||||
WikiPathways | GPCRs, Class C Metabotropic glutamate, pheromone | |||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1405). | |||
REF 2 | Characterization of [(3)H]-LY354740 binding to rat mGlu2 and mGlu3 receptors expressed in CHO cells using semliki forest virus vectors. Neuropharmacology. 2000 Jul 24;39(10):1700-6. |
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