Drug Information
Drug General Information | Top | |||
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Drug ID |
D02EZF
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Former ID |
DIB020963
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Drug Name |
SMP-797
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Synonyms |
compound 22b [PMID: 16242323]
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C34H43N5O4
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Canonical SMILES |
CCCCN1C2=C(C=CC=N2)C(=C(C1=O)NC(=O)NC3=C(C=C(C=C3C(C)C)N)C(C)C)C4=CC(=CC=C4)OCCCO
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InChI |
1S/C34H43N5O4/c1-6-7-15-39-32-26(13-9-14-36-32)29(23-11-8-12-25(18-23)43-17-10-16-40)31(33(39)41)38-34(42)37-30-27(21(2)3)19-24(35)20-28(30)22(4)5/h8-9,11-14,18-22,40H,6-7,10,15-17,35H2,1-5H3,(H2,37,38,42)
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InChIKey |
HNRUUMLUBDTZHX-UHFFFAOYSA-N
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CAS Number |
CAS 437763-85-4
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Liver carboxylesterase (CES1) | Target Info | Modulator | [2] |
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
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REF 1 | Synthesis and biological activity of novel 4-phenyl-1,8-naphthyridin-2(1H)-on-3-yl ureas: potent acyl-CoA:cholesterol acyltransferase inhibitor wit... Bioorg Med Chem Lett. 2006 Jan 1;16(1):44-8. | |||
REF 2 | Company report (Dainippon Sumitomo Pharma) |
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