Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02CWR
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| Former ID |
DNC014822
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| Drug Name |
OXYBENZONE
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| Synonyms |
oxybenzone; 131-57-7; 2-HYDROXY-4-METHOXYBENZOPHENONE; Benzophenone-3; Oxybenzon; 4-Methoxy-2-hydroxybenzophenone; 2-Benzoyl-5-methoxyphenol; (2-hydroxy-4-methoxyphenyl)(phenyl)methanone; Oxybenzonum; Oxibenzona; Anuvex; Methanone, (2-hydroxy-4-methoxyphenyl)phenyl-; Chimassorb 90; Uvinul 9; Advastab 45; Sunscreen UV-15; Syntase 62; Uvistat 24; Cyasorb UV 9; Usaf cy-9; Spectra-sorb UV 9; Escalol 567; Ongrostab HMB; Oxybenzonum [INN-Latin]; Uvinul M40; Oxibenzonum; Oxibenzona [INN-Spanish]; HMBP; Cyasorb UV 9 Light Absorber
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C14H12O3
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| Canonical SMILES |
COC1=CC(=C(C=C1)C(=O)C2=CC=CC=C2)O
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| InChI |
1S/C14H12O3/c1-17-11-7-8-12(13(15)9-11)14(16)10-5-3-2-4-6-10/h2-9,15H,1H3
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| InChIKey |
DXGLGDHPHMLXJC-UHFFFAOYSA-N
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| CAS Number |
CAS 131-57-7
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:34283
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hormone sensitive lipase (LIPE) | Target Info | Inhibitor | [1] |
| BioCyc | Triacylglycerol degradation | |||
| KEGG Pathway | cAMP signaling pathway | |||
| AMPK signaling pathway | ||||
| Insulin signaling pathway | ||||
| Panther Pathway | Triacylglycerol metabolism | |||
| Reactome | Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis | |||
| WikiPathways | Insulin Signaling | |||
| Triacylglyceride Synthesis | ||||
| Lipid digestion, mobilization, and transport | ||||
| Adipogenesis | ||||
| Fatty Acid Beta Oxidation | ||||
| AMPK Signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Combining ligand-based pharmacophore modeling, quantitative structure-activity relationship analysis and in silico screening for the discovery of n... J Med Chem. 2008 Oct 23;51(20):6478-94. | |||
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