Drug Information
Drug General Information | Top | |||
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Drug ID |
D02CTS
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Former ID |
DCL001219
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Drug Name |
Ospemifene
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Synonyms |
Ospemifene; 128607-22-7; Osphena; FC-1271a; Deamino-hydroxytoremifene; Fc-1271; 2-(4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy)ethanol; UNII-B0P231ILBK; CCRIS 9205; B0P231ILBK; CHEBI:73275; 2-(p-((Z)-4-Chloro-1,2-diphenyl-1-butenyl)phenoxy)ethanol; senshio; Ethanol, 2-[4-[(1Z)-4-chloro-1,2-diphenyl-1-butenyl]phenoxy]-; 2-{4-[(1Z)-4-chloro-1,2-diphenylbut-1-en-1-yl]phenoxy}ethanol; Ophena; Ospemifene [USAN:INN:BAN]; Deaminotoremifene; Osphena (TN); Deaminohydroxytoremifene; AC1MI19T; C24H23ClO2
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Drug Type |
Small molecular drug
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Indication | Dyspareunia [ICD-11: GA12; ICD-10: F52.6, N94.1] | Approved | [1], [2] | |
Postmenopausal vaginal atrophy [ICD-11: GA30.2; ICD-10: N95.2; ICD-9: 627.3] | Phase 3 | [1], [3] | ||
Company |
Shionogi; QuatRx
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Structure |
Download2D MOL |
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Formula |
C24H23ClO2
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Canonical SMILES |
C1=CC=C(C=C1)C(=C(C2=CC=CC=C2)C3=CC=C(C=C3)OCCO)CCCl
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InChI |
1S/C24H23ClO2/c25-16-15-23(19-7-3-1-4-8-19)24(20-9-5-2-6-10-20)21-11-13-22(14-12-21)27-18-17-26/h1-14,26H,15-18H2/b24-23-
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InChIKey |
LUMKNAVTFCDUIE-VHXPQNKSSA-N
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CAS Number |
CAS 128607-22-7
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PubChem Compound ID | ||||
PubChem Substance ID | ||||
ChEBI ID |
CHEBI:73275
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ADReCS Drug ID | BADD_D01630 | |||
SuperDrug ATC ID |
G03XC05
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References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7349). | |||
REF 2 | Radium 223 dichloride for prostate cancer treatment. Drug Des Devel Ther. 2017 Sep 6;11:2643-2651. | |||
REF 3 | Clinical pipeline report, company report or official report of Shionogi (2011). |
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