Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D02BPI
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| Former ID |
DNC001414
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| Drug Name |
TCPOBOP
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| Synonyms |
tcpobop; 76150-91-9; 1,4-Bis[2-(3,5-dichloropyridyloxy)]benzene; 1,4-BDPOB; CCRIS 3521; 2,2'-[1,4-phenylenebis(oxy)]bis(3,5-dichloropyridine); 1,4-Bis(2-(3,5-dichloropyridyloxy))benzene; 3,5-DICHLORO-2-{4-[(3,5-DICHLOROPYRIDIN-2-YL)OXY]PHENOXY}PYRIDINE; MLS000532100; 2,2'-[benzene-1,4-diylbis(oxy)]bis(3,5-dichloropyridine); 1,4-Bis-[2-(3,5-dichloropyridyloxy)]benzene; 1,4-bis((3,5-dichloropyridin-2-yl)oxy)benzene; Pyridine,2,2'-[1,4-phenylenebis(oxy)]bis[3,5-dichloro-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H8Cl4N2O2
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| Canonical SMILES |
C1=CC(=CC=C1OC2=C(C=C(C=N2)Cl)Cl)OC3=C(C=C(C=N3)Cl)Cl
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| InChI |
1S/C16H8Cl4N2O2/c17-9-5-13(19)15(21-7-9)23-11-1-2-12(4-3-11)24-16-14(20)6-10(18)8-22-16/h1-8H
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| InChIKey |
BAFKRPOFIYPKBQ-UHFFFAOYSA-N
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| CAS Number |
CAS 76150-91-9
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| PubChem Compound ID | ||||
| PubChem Substance ID |
585698, 1928128, 3147264, 3295751, 4405152, 7890713, 8153308, 11111861, 14735746, 14903727, 17405730, 24278723, 26753662, 26753663, 26759612, 29224434, 47365334, 47662437, 48413304, 50032849, 50107099, 50107100, 50637700, 53778280, 53788842, 53800504, 56314443, 56314444, 57322746, 57672487, 81097025, 85231247, 88155323, 90341451, 92303309, 93167134, 103107812, 103648135, 104309080, 105574140, 117459274, 117468981, 121361993, 124750293, 124881573, 124881574, 124881575, 124881576, 125024433, 125786933
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Orphan nuclear receptor NR1I3 (NR1I3) | Target Info | Agonist | [2] |
| Pathway Interaction Database | Glucocorticoid receptor regulatory network | |||
| WikiPathways | Nuclear Receptors in Lipid Metabolism and Toxicity | |||
| Nuclear Receptors Meta-Pathway | ||||
| Constitutive Androstane Receptor Pathway | ||||
| Drug Induction of Bile Acid Pathway | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2756). | |||
| REF 2 | The nuclear receptor CAR is a regulator of thyroid hormone metabolism during caloric restriction. J Biol Chem. 2004 May 7;279(19):19832-8. | |||
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