Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D02ANJ
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| Former ID |
DIB005511
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| Drug Name |
NZ-107
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| Synonyms |
4-Bromo-5-(3-ethoxy-4-methoxybenzylamino)pyridazin-3(2H)-one
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| Drug Type |
Small molecular drug
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| Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Discontinued in Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C14H16BrN3O3
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| Canonical SMILES |
CCOC1=C(C=CC(=C1)CNC2=C(C(=O)NN=C2)Br)OC
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| InChI |
1S/C14H16BrN3O3/c1-3-21-12-6-9(4-5-11(12)20-2)7-16-10-8-17-18-14(19)13(10)15/h4-6,8H,3,7H2,1-2H3,(H2,16,18,19)
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| InChIKey |
KNIKAZNCSPYOED-UHFFFAOYSA-N
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| CAS Number |
CAS 107186-52-7
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukotriene receptor (LTR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000068) | |||
| REF 2 | Effects of NZ-107 on tracheal responses to adenosine in the guinea pig. Jpn J Pharmacol. 1991 May;56(1):79-84. | |||
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