Drug Information
Drug General Information | Top | |||
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Drug ID |
D02ANG
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Former ID |
DNC012508
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Drug Name |
(2-Amino-4,5-dihydro-thiazol-4-yl)-acetic acid
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Synonyms |
CHEMBL79325; 2-(2-Amino-2-thiazolin-4-yl)acetic acid; AC1NQ6SQ; SCHEMBL2711624; 2-(2-amino-4,5-dihydro-1,3-thiazol-4-yl)acetic Acid; ANCWBXJZUCHVHL-UHFFFAOYSA-N
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C5H8N2O2S
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Canonical SMILES |
C1C(N=C(S1)N)CC(=O)O
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InChI |
1S/C5H8N2O2S/c6-5-7-3(2-10-5)1-4(8)9/h3H,1-2H2,(H2,6,7)(H,8,9)
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InChIKey |
ANCWBXJZUCHVHL-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Retrograde endocannabinoid signaling | ||||
GABAergic synapse | ||||
Morphine addiction | ||||
Nicotine addiction | ||||
Reactome | Ligand-gated ion channel transport | |||
GABA A receptor activation | ||||
WikiPathways | SIDS Susceptibility Pathways | |||
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
Iron uptake and transport |
References | Top | |||
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REF 1 | ( )-2-amino-2-thiazoline-4-ethanoic acid; a novel, specific GABAA receptor agonist. Bioorg. Med. Chem. Lett. 1(5):247-248 (1991). |
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