Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01ZOB
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| Former ID |
DNCL001870
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| Drug Name |
Terguride
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| Synonyms |
terguride; Dironyl; 37686-84-3; trans-Dihydrolisuride; (+)-Terguride; (5R,8S,10R)-Terguride; S(+)-Terguride; UNII-21OJT43Q88; TDHL; Transdihydrolisuride; (+)-(5R,8S,10R)-Terguride; CHEMBL73151; MLS000069833; Terguride [INN]; 21OJT43Q88; Terguridum [Latin]; Tergurida [Spanish]; SMR000058934; 9,10-alpha-Dihydrolisuride; 1,1-diethyl-3-(6-methyl-8alpha-ergolinyl)urea; Terguridum; Tergurida; Tergurid; EINECS 253-624-2; BRN 0766582; ZK 31224; trans-Dihydro Lisuride; 6-Methyl-8alpha-(diethylcarbamoylamino)ergoline
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| Drug Type |
Small molecular drug
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| Indication | Pulmonary arterial hypertension [ICD-11: BB01.0; ICD-9: 416] | Phase 2 | [1], [2] | |
| Company |
ErgoNex Pharma; Pfizer
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H28N4O
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| Canonical SMILES |
CCN(CC)C(=O)NC1CC2C(CC3=CNC4=CC=CC2=C34)N(C1)C
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| InChI |
1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1
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| InChIKey |
JOAHPSVPXZTVEP-YXJHDRRASA-N
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| CAS Number |
CAS 37686-84-3
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7848411, 10299440, 11466973, 11468093, 11486805, 11533045, 12013758, 14753698, 24278800, 36887095, 47365364, 47515474, 48035299, 48334658, 49699375, 57404568, 75574382, 92125876, 103272403, 103914554, 103928787, 104631021, 124800150, 124893608, 134223771, 135651246, 136112725, 137249381, 141724362, 144204835, 162226496, 164840227, 175268337, 179150405, 223554845, 224890546, 226513252, 241066802
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| ChEBI ID |
CHEBI:32193
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| SuperDrug ATC ID |
G02CB06
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 56). | |||
| REF 2 | Clinical pipeline report, company report or official report of Pfizer. | |||
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