Drug Information
Drug General Information | Top | |||
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Drug ID |
D01UFM
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Former ID |
DNC009100
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Drug Name |
N-cyclohexyl-2-oxo-2H-chromene-3-carboxamide
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Synonyms |
N-cyclohexyl-2-oxo-2H-chromene-3-carboxamide; N-cyclohexyl-2-oxochromene-3-carboxamide; 2-Oxo-2H-chromene-3-carboxylic acid cyclohexylamide; 4021-23-2; BAS 00837943; ChemDiv2_003298; 3-carboxamido coumarin, 1; AC1Q5N8P; AC1LF7K7; Oprea1_254332; Oprea1_273725; CHEMBL472080; BDBM29152; CTK1C9968; DTXSID70352366; MolPort-001-028-458; ZINC130287; HMS1378F20; CCG-15837; STK408165; AKOS000533315; MCULE-8945496486; N-cyclohexyl(2-oxochromen-3-yl)carboxamide; EU-0035943; ST50185340; SR-01000410421; SR-01000410421-1
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C16H17NO3
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Canonical SMILES |
C1CCC(CC1)NC(=O)C2=CC3=CC=CC=C3OC2=O
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InChI |
1S/C16H17NO3/c18-15(17-12-7-2-1-3-8-12)13-10-11-6-4-5-9-14(11)20-16(13)19/h4-6,9-10,12H,1-3,7-8H2,(H,17,18)
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InChIKey |
KUWSPPXPGQEHSQ-UHFFFAOYSA-N
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CAS Number |
CAS 4021-23-2
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Monoamine oxidase type B (MAO-B) | Target Info | Inhibitor | [1] |
BioCyc | Superpathway of tryptophan utilization | |||
Tryptophan degradation via tryptamine | ||||
Dopamine degradation | ||||
Putrescine degradation III | ||||
Noradrenaline and adrenaline degradation | ||||
KEGG Pathway | Glycine, serine and threonine metabolism | |||
Arginine and proline metabolism | ||||
Histidine metabolism | ||||
Tyrosine metabolism | ||||
Phenylalanine metabolism | ||||
Tryptophan metabolism | ||||
Drug metabolism - cytochrome P450 | ||||
Metabolic pathways | ||||
Serotonergic synapse | ||||
Dopaminergic synapse | ||||
Cocaine addiction | ||||
Amphetamine addiction | ||||
Alcoholism | ||||
Panther Pathway | Adrenaline and noradrenaline biosynthesis | |||
5-Hydroxytryptamine degredation | ||||
Dopamine receptor mediated signaling pathway | ||||
Pathway Interaction Database | Alpha-synuclein signaling | |||
WikiPathways | Tryptophan metabolism | |||
Dopamine metabolism | ||||
Phase 1 - Functionalization of compounds |
References | Top | |||
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REF 1 | Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins. J Med Chem. 2009 Apr 9;52(7):1935-42. |
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