Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01TSX
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| Former ID |
DNC013349
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| Drug Name |
(R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
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| Synonyms |
(R)-1-(4-Iodo-2,5-dimethoxyphenyl)propan-2-amine; CHEMBL134519; R-DOI; Lopac0_000478; GTPL157; (R)-DOI; SCHEMBL713061; ZINC2516053; PDSP2_001372; Benzeneethanamine, 4-iodo-2,5-dimethoxy-alpha-methyl-, (alphaR)-; BDBM50133231; PDSP1_001388; CCG-204569; NCGC00162167-01; AJ-36945; 82864-06-0; (2R)-1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine; (r)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane; (R)-2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine; (R)-2-(4-Iodo-2,5-dimethoxy-phenyl)-1-methyl-ethylamine; UNII-OOM10GW9UE
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H16INO2
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| Canonical SMILES |
CC(CC1=CC(=C(C=C1OC)I)OC)N
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| InChI |
1S/C11H16INO2/c1-7(13)4-8-5-11(15-3)9(12)6-10(8)14-2/h5-7H,4,13H2,1-3H3/t7-/m1/s1
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| InChIKey |
BGMZUEKZENQUJY-SSDOTTSWSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity. Bioorg Med Chem Lett. 2007 Jun 1;17(11):2998-3002. | |||
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