Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01TGH
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| Former ID |
DIB000255
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| Drug Name |
PF-572778
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| Synonyms |
PF-00572778
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| Indication | Generalized anxiety disorder [ICD-11: 6B00; ICD-10: F41.1] | Terminated | [1] | |
| Company |
Pfizer Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Corticotropin-releasing factor receptor 2 (CRHR2) | Target Info | Modulator | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Panther Pathway | Cortocotropin releasing factor receptor signaling pathway | |||
| Reactome | Class B/2 (Secretin family receptors) | |||
| G alpha (s) signalling events | ||||
| WikiPathways | GPCRs, Class B Secretin-like | |||
| Corticotropin-releasing hormone | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025528) | |||
| REF 2 | WO patent application no. 2013,1603,15, Genetic predictors of response to treatment with crhr1 antagonists. | |||
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