Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01REJ
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| Former ID |
DIB009063
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| Drug Name |
VBY- 891
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| Synonyms |
VBY-891
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| Indication | Autoimmune diabetes [ICD-11: 5A10] | Phase 1 | [1] | |
| Company |
Virobay Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin S (CTSS) | Target Info | Modulator | [2] |
| KEGG Pathway | Lysosome | |||
| Phagosome | ||||
| Antigen processing and presentation | ||||
| Tuberculosis | ||||
| NetPath Pathway | Leptin Signaling Pathway | |||
| IL2 Signaling Pathway | ||||
| Reactome | Endosomal/Vacuolar pathway | |||
| Degradation of the extracellular matrix | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Class I MHC mediated antigen processing & presentation | |||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT01947738) Safety Study of VBY-891 in Healthy Volunteers After Single or Multiple (7 Days) of Oral Dosing (VBY891P1). U.S. National Institutes of Health. | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2353). | |||
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