Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01OXH
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| Former ID |
DIB001342
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| Drug Name |
ASP-7035
|
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| Indication | Nocturia [ICD-11: MF55; ICD-10: R35] | Phase 2 | [1] | |
| Company |
Astellas Pharma Inc
|
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| Structure |
 |
Download2D MOL |
||
| Formula |
C25H23F7N2O4
|
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| Canonical SMILES |
CC(COC1=CC(=C(C=C1)C(=O)N2CCC(C(=CC(=O)NCCO)C3=C2C=CC(=C3)F)(F)F)C(F)(F)F)F
|
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| InChI |
1S/C25H23F7N2O4/c1-14(26)13-38-16-3-4-17(20(11-16)25(30,31)32)23(37)34-8-6-24(28,29)19(12-22(36)33-7-9-35)18-10-15(27)2-5-21(18)34/h2-5,10-12,14,35H,6-9,13H2,1H3,(H,33,36)/b19-12-/t14-/m1/s1
|
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| InChIKey |
VSXSHTIGQAUGMW-VCRXTVNUSA-N
|
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| CAS Number |
CAS 790694-26-7
|
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Vasopressin V2 receptor (V2R) | Target Info | Agonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Vasopressin-regulated water reabsorption | ||||
| Pathwhiz Pathway | Vasopressin Regulation of Water Homeostasis | |||
| Pathway Interaction Database | Arf6 trafficking events | |||
| Reactome | Vasopressin-like receptors | |||
| G alpha (s) signalling events | ||||
| Vasopressin regulates renal water homeostasis via Aquaporins | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Regulation of Water Balance by Renal Aquaporins | ||||
| Peptide GPCRs | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030285) | |||
| REF 2 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030285) | |||
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