Drug Information
Drug General Information | Top | |||
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Drug ID |
D01NTN
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Former ID |
DNC005483
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Drug Name |
3-(3,5-Dibromo-4-hexyloxy-phenyl)-propionic acid
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Synonyms |
SCHEMBL4895878; CHEMBL195556; BDBM18906; ZINC13643210; 3,5-Dibromo-4-alkoxyphenylalkanoic Acid, 9i; 3-[3,5-dibromo-4-(hexyloxy)phenyl]propanoic acid
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C15H20Br2O3
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Canonical SMILES |
CCCCCCOC1=C(C=C(C=C1Br)CCC(=O)O)Br
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InChI |
1S/C15H20Br2O3/c1-2-3-4-5-8-20-15-12(16)9-11(10-13(15)17)6-7-14(18)19/h9-10H,2-8H2,1H3,(H,18,19)
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InChIKey |
FVDRTJXVCUAOCA-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Thyroid hormone receptor alpha (THRA) | Target Info | Inhibitor | [1] |
Thyroid hormone receptor beta (THRB) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Thyroid hormone signaling pathway | ||||
Pathway Interaction Database | RXR and RAR heterodimerization with other nuclear receptor | |||
Reactome | Nuclear Receptor transcription pathway | |||
WikiPathways | Endochondral Ossification | |||
Nuclear Receptors | ||||
SIDS Susceptibility Pathways | ||||
Hematopoietic Stem Cell Differentiation |
References | Top | |||
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REF 1 | Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor. J Med Chem. 2005 May 5;48(9):3114-7. |
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