Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01MWF
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| Former ID |
DIB015969
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| Drug Name |
GTx-878
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| Synonyms |
Estrogen receptor beta agonist (prostatitis/BPH), GTx
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|
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| Indication | Prostate hyperplasia [ICD-11: GA90; ICD-10: N40] | Investigative | [1] | |
| Company |
GTx Inc
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Estrogen receptor beta (ESR2) | Target Info | Agonist | [1] |
| KEGG Pathway | Estrogen signaling pathway | |||
| Prolactin signaling pathway | ||||
| Pathway Interaction Database | Plasma membrane estrogen receptor signaling | |||
| Validated nuclear estrogen receptor beta network | ||||
| Validated nuclear estrogen receptor alpha network | ||||
| Reactome | Nuclear Receptor transcription pathway | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Ovarian Infertility Genes | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 621). | |||
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