Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01MKD
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| Drug Name |
Phenylalanine derivative 1
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| Synonyms |
PMID27998201-Compound-21
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| Drug Type |
Small molecular drug
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| Indication | Glioma [ICD-11: 2A00.0; ICD-9: 191] | Patented | [1] | |
| Structure |
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Download2D MOL |
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cathepsin L (CTSL) | Target Info | Inhibitor | [1] |
| Cathepsin S (CTSS) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Cathepsin L (CTSL) | Target's Patent Info | [1] | |
| Cathepsin S (CTSS) | Target's Patent Info | [1] | ||
| KEGG Pathway | Lysosome | |||
| Phagosome | ||||
| Antigen processing and presentation | ||||
| Proteoglycans in cancer | ||||
| Rheumatoid arthritis | ||||
| Tuberculosis | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Leptin Signaling Pathway | ||||
| IL2 Signaling Pathway | ||||
| Reactome | Endosomal/Vacuolar pathway | |||
| Collagen degradation | ||||
| Degradation of the extracellular matrix | ||||
| Trafficking and processing of endosomal TLR | ||||
| Assembly of collagen fibrils and other multimeric structures | ||||
| MHC class II antigen presentation | ||||
| WikiPathways | Primary Focal Segmental Glomerulosclerosis FSGS | |||
| Class I MHC mediated antigen processing & presentation | ||||
| Trafficking and processing of endosomal TLR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Cathepsin B and L inhibitors: a patent review (2010 - present).Expert Opin Ther Pat. 2017 Jun;27(6):643-656. | |||
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