Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01GWH
|
|||
| Former ID |
DNC013296
|
|||
| Drug Name |
N-(1-(4-phenylbutyl)piperidin-4-yl)-2-naphthamide
|
|||
| Synonyms |
CHEMBL229025; N-(1-(4-phenylbutyl)piperidin-4-yl)-2-naphthamide
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C26H30N2O
|
|||
| Canonical SMILES |
C1CN(CCC1NC(=O)C2=CC3=CC=CC=C3C=C2)CCCCC4=CC=CC=C4
|
|||
| InChI |
1S/C26H30N2O/c29-26(24-14-13-22-11-4-5-12-23(22)20-24)27-25-15-18-28(19-16-25)17-7-6-10-21-8-2-1-3-9-21/h1-5,8-9,11-14,20,25H,6-7,10,15-19H2,(H,27,29)
|
|||
| InChIKey |
XYKZGGUQORZZTO-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the ... Bioorg Med Chem Lett. 2007 Mar 15;17(6):1565-9. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.