Drug Information
Drug General Information | Top | |||
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Drug ID |
D01GLR
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Former ID |
DNC002142
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Drug Name |
ISIS 103387
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Drug Type |
Antisense drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Company |
Isis Pharmaceuticals
|
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | DUSP8 messenger RNA (DUSP8 mRNA) | Target Info | . | [1] |
KEGG Pathway | MAPK signaling pathway | |||
NetPath Pathway | IL2 Signaling Pathway | |||
TCR Signaling Pathway | ||||
Pathway Interaction Database | Regulation of p38-alpha and p38-beta | |||
ATF-2 transcription factor network | ||||
Reactome | RAF-independent MAPK1/3 activation | |||
Negative regulation of MAPK pathway |
References | Top | |||
---|---|---|---|---|
REF 1 | US patent application no. 6,482,644, Antisense modulation of dual specific phosphatase 8 expression. |
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