Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01DSP
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| Former ID |
DAP001160
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| Drug Name |
Cephapirin
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| Synonyms |
CEPR; Cefa; Cefadyl; Cefapirin; Cefapirina; Cefapirine; Cefapirinum; Cefaprin; Cephapirine; Metricure; CEPHAPIRIN SODIUM; Cefaprinsodium; Cephapirin Monosodium Salt; ANTIBIOTIC BL-P1322; BL-P 1322; Cefa-ak; Cefadyl (TN); Cefapirin (BAN); Cefapirin [INN:BAN]; Cefapirina [INN-Spanish]; Cefapirine [INN-French]; Cefapirinum [INN-Latin]; Metricure (TN); (6R,7R)-3-(Acetoxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-en-2-carbonsaeure; (6R,7R)-3-(acetyloxymethyl)-8-oxo-7-[(2-pyridin-4-ylsulfanylacetyl)amino]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-{[(pyridin-4-ylthio)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; (6R,7R)-3-acetoxymethyl-7-[(pyridin-4-ylsulfanyl)acetamido]-3,4-didehydrocepham-4-carboxylic acid; 3-(Hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamidol-5-thia-1-azabicyclo(4.2.0)oct-2-en-2carbonsaeure acetat; 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 3-(hydroxymethyl)-8-oxo-7-(2-(4-pyridylthio)acetamido)-, acetate (ester); 7-(2-(4-Pyridylthio)acetamido)cephalosporanic acid
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| Drug Type |
Small molecular drug
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| Indication | Sepsis [ICD-11: 1G40-1G41; ICD-9: 995.91] | Approved | [1], [2] | |
| Therapeutic Class |
Antibiotics
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| Structure |
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Download2D MOL |
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| Formula |
C17H17N3O6S2
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| Canonical SMILES |
CC(=O)OCC1=C(N2C(C(C2=O)NC(=O)CSC3=CC=NC=C3)SC1)C(=O)O
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| InChI |
1S/C17H17N3O6S2/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25)/t13-,16-/m1/s1
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| InChIKey |
UQLLWWBDSUHNEB-CZUORRHYSA-N
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| CAS Number |
CAS 21593-23-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9113, 602885, 8171717, 11335217, 11360456, 11362966, 11365528, 11368090, 11371285, 11373879, 11376252, 11461428, 11466879, 11467999, 11483822, 11486518, 11487919, 11490149, 11492085, 11493926, 15452100, 34672911, 46505227, 47440073, 47515148, 47588824, 47885243, 48184822, 48415744, 50050995, 51091940, 57310975, 74511317, 87323458, 103590583, 104133804, 104308908, 117600530, 124766406, 129405974, 134223575, 134338405, 134995684, 137003415, 140396434, 152035918, 160849694, 160964473, 162497207, 175266904
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| ChEBI ID |
CHEBI:554446
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| SuperDrug ATC ID |
J01DB08
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| SuperDrug CAS ID |
cas=021593237
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial Penicillin binding protein (Bact PBP) | Target Info | Binder | [3] |
| References | Top | |||
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| REF 1 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (ANDA) 062720. | |||
| REF 2 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 3 | The formation of functional penicillin-binding proteins. J Biol Chem. 1975 Aug 25;250(16):6578-85. | |||
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