Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01DSL
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| Drug Name |
Triptolidenol analog 1
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| Synonyms |
PMID26882240-Compound-38
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| Drug Type |
Small molecular drug
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| Company |
Institute of Materia Medica, Chinese Academy of Medical Sciences, Peop. Rep. China
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| Structure |
 |
Download2D MOL |
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| Formula |
C29H29FO8
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| Canonical SMILES |
CC12CCC3=C(C1CC4C5(C26C(O6)C7C(C5OC(=O)C=CC8=CC=C(C=C8)F)(O7)C(C)(C)O)O4)COC3=O
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| InChI |
1S/C29H29FO8/c1-25(2,33)28-21(37-28)22-29(38-22)26(3)11-10-16-17(13-34-23(16)32)18(26)12-19-27(29,36-19)24(28)35-20(31)9-6-14-4-7-15(30)8-5-14/h4-9,18-19,21-22,24,33H,10-13H2,1-3H3/b9-6+/t18-,19-,21-,22-,24-,26-,27+,28-,29+/m0/s1
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| InChIKey |
FVQHGGQECDTHSW-YZAYWNIQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Hypoxia-inducible factor 1 (HIF-1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Hypoxia-inducible factor 1 (HIF-1) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Hypoxia-inducible factor (HIF) inhibitors: a patent survey (2011-2015).Expert Opin Ther Pat. 2016;26(3):309-22. | |||
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