Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D01BCL
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| Former ID |
DNC014359
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| Drug Name |
(+/-)-2-Amino-1,2,3,4-tetrahydro-2-naphthoic acid
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| Synonyms |
2-Aminotetralin-2-carboxylic acid; 74444-77-2; D,L-2-Aminotetralin-2-carboxylic acid; 2-amino-1,2,3,4-tetrahydronaphthalene-2-carboxylic acid; 6331-63-1; CHEMBL8708; 2-amino-3,4-dihydro-1H-naphthalene-2-carboxylic acid; 2-Amino-1,2,3,4-tetrahydro-naphthalene-2-carboxylic acid; 2-AMINO-1,2,3,4-TETRAHYDRO-2-NAPHTHALENECARBOXYLIC ACID; 2-Naphthalenecarboxylic acid, 2-amino-1,2,3,4-tetrahydro-; ACMC-20apiw; ACMC-20apfh; CB 1647; AC1L5ULH; SCHEMBL268919; (+/-)-2-Amino-1,2,3,4-tetrahydro-2-naphthoic acid; NIOSH/QL2303010
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H13NO2
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| Canonical SMILES |
C1CC(CC2=CC=CC=C21)(C(=O)O)N
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| InChI |
1S/C11H13NO2/c12-11(10(13)14)6-5-8-3-1-2-4-9(8)7-11/h1-4H,5-7,12H2,(H,13,14)
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| InChIKey |
CDULPPOISZOUTK-UHFFFAOYSA-N
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| CAS Number |
CAS 74444-77-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Large neutral amino acids transporter 1 (SLC7A5) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Central carbon metabolism in cancer | |||
| NetPath Pathway | IL2 Signaling Pathway | |||
| TGF_beta_Receptor Signaling Pathway | ||||
| Pathwhiz Pathway | Kidney Function | |||
| Leucine Stimulation on Insulin Signaling | ||||
| Reactome | Basigin interactions | |||
| Amino acid transport across the plasma membrane | ||||
| WikiPathways | Nuclear Receptors Meta-Pathway | |||
| Aryl Hydrocarbon Receptor Pathway | ||||
| Transport of inorganic cations/anions and amino acids/oligopeptides | ||||
| Cell surface interactions at the vascular wall | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Regiospecific and conformationally restrained analogs of melphalan and DL-2-NAM-7 and their affinities for the large neutral amino acid transporter... Bioorg Med Chem Lett. 2010 Jun 15;20(12):3688-91. | |||
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