Drug Information
Drug General Information | Top | |||
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Drug ID |
D01AFG
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Former ID |
DNCL002642
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Drug Name |
RG7414
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Indication | Colorectal cancer [ICD-11: 2B91.Z] | Discontinued in Phase 2 | [1] | |
Non-small-cell lung cancer [ICD-11: 2C25.Y] | Discontinued in Phase 2 | [1] | ||
Company |
Genentech
|
Target and Pathway | Top | |||
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Target(s) | Epidermal growth factor-like protein 7 (EGFL7) | Target Info | Modulator | [2] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800030998) | |||
REF 2 | Anti-EGFL7 antibodies enhance stress-induced endothelial cell death and anti-VEGF efficacy. J Clin Invest. 2013 September 3; 123(9): 3997-4009. |
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